Upsquatulate Posted in U Best definition Upsquatulate To leave with great haste, usually from a seated or prone position. To ensure that my foray was a true one-night-stand, I decided to upsquatulate while she was in the shower. How satisfied are you with the definition? Looking for Upsquatulate meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 59 times.