Best definition
Abbreviation for “Up For”.
Often used when enquiring about the possiblity of sexual relations with a member of the

opposite sex.

Dude: “Hey baby, upfa?”

Chick: “No”

Dude: “Bitch!”
upfa: define #2
(Pronounced oopfa) Stands for Upper Pussy Fat Area. Or the fat that hangs over a woman’s vagina.
Dude, look at Mrs. Walkers UPFA!
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