muthafuckaz Posted in M Best definition muthafuckaz A person, often of African origin, who fucks his/her mother, usually in the ghetto. Yo yo, my muthafuckaz, we be needin’ a forty…. Beeeyotch! How satisfied are you with the definition? Looking for muthafuckaz meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 92 times.