Best definition
– abbreviation forMake the Shit Up

Utilized by Corporate Americans who wait until the last day to turn in PPE’s, PTE’s, PMP’s and other performance evaluations and team goals; MTSU, or Make the Shit Up, can be a useful tool when completing a variety of forms that you deem a complete waste of your time.
MTSU: define #2
Middle Tennessee State University.
I got my degree in meth poduction at MTSU.
MTSU: define #3
1. Middle Tennessee State University. A mediocre at best 4 year university in Murfreesboro, Tennessee.

2. Many Teeth Stacked Up. Used to describe a redneck or piece of trash that has crooked, fucked up teeth.

MTSU is the biggest excuse for a college ever!

Look at that redneck bitch, she got MTSU!!!

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