Best definition
stands for “Mad Fucked Up”

Roger: I heard you called that girl a bitch.

Tina: I did!

Roger: Wow MFU, she’s moving tomorrow.
mfu: define #2
acronym for ‘mad fucked up’
Bob: Damn i’d sure like to cut Lisha’s cake.

Joe: Dude, Lisha’s your best friend’s girlfriend. MFU!
mfu: define #3
Short for Mother Fucker
You’re such a Mfu
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