MacGuffles Posted in M Best definition MacGuffles The absolute most awesome person alive. Anyone who has this name is also considered a god. He/She has a destiny of lots of money. MacGuffles is also a state of mind that’s better than NIRVANA. MacGuffles How satisfied are you with the definition? Looking for MacGuffles meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 57 times.