Luiseño Posted in L Best definition LuiseÃÂ±o LuiseÃÂ±o is a Native American Tribe in Southern California. The main reservation for the LuiseÃÂ±o is Rincon Reservation. I live on the Rincon Reservation ( or Rincon Rez ) and I’m part LuiseÃÂ±o blood. How satisfied are you with the definition? Looking for Luiseño meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 66 times.