Loosen up my buttons Posted in L Best definition Loosen up my buttons An “ebonics” term reffering to taking one’s clothes off in preparation for “explicit activities”. Hey Chimp, loosen up my buttons. *provocative wink* How satisfied are you with the definition? Looking for Loosen up my buttons meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 22 times.