Lollersox Posted in L Best definition Lollersox Lollersox; derivation: ‘lol’ (acronym of ‘laugh out loud’)”to laugh one’s socks off”; to proclaim one’s socks have been blown off by laughter. “Lollersox!!”; “I lollersox’d!” How satisfied are you with the definition? Looking for Lollersox meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 18 times.