Lokest Posted in L Best definition Lokest an adjective meaning the Craziest, derived from the spanish word “Loco”….that gangsta mentality…ya dig? Yo, that kid Lui T is the Lokest cat in the 707 area, he’ll go berserk on a buster. watch yaself! How satisfied are you with the definition? Looking for Lokest meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 63 times.