Lock That Shit Down Posted in L Best definition Lock That Shit Down To take control of situation. To get in charge of something. Lock That Shit Down can be used to describe taking control of the situation with your woman. “Son, you need to lock that shit down, pronto” How satisfied are you with the definition? Looking for Lock That Shit Down meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 104 times.