little hommie Posted in L Best definition little hommie a thug ass muthafucka who knows how to smoke weed and keep a heap of it most of the time. hey dude little hommie is aweome dont say that to him he can kick your ass and im not helping you. How satisfied are you with the definition? Looking for little hommie meaning? Delighted that you discovered the greatest determine on our web site! Recently this definition was actually observed 95 times.